Blar i Bergen Open Research Archive på forfatter "Lien, Hilde Eide"

Viser treff 1-4 av 4

    • High-dimensional immunotyping of tumors grown in obese and non-obese mice 

      Wogsland, Cara Ellen; Lien, Hilde Eide; Pedersen, Line; Hanjra, Pahul; Grøndal, Sturla Magnus; Brekken, Rolf A; Lorens, James Bradley; Halberg, Nils Henrik (Journal article; Peer reviewed, 2021)
      Obesity is a disease characterized by chronic low-grade systemic inflammation and has been causally linked to the development of 13 cancer types. Several studies have been undertaken to determine whether tumors evolving ...

    • Mismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value 

      Berg, Hege Fredriksen; Engerud, Hilde Renate; Myrvold, Madeleine; Lien, Hilde Eide; Hjelmeland, Marta Espevold; Halle, Mari Kyllesø; Woie, Kathrine; Høivik, Erling Andre; Haldorsen, Ingfrid S.; Vintermyr, Olav Karsten; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2022)
      Background The endometrial cancer mismatch repair (MMR) deficient subgroup is defined by loss of MSH6, MSH2, PMS2 or MLH1. We compare MMR status in paired preoperative and operative samples and investigate the prognostic ...

    • Patient-derived organoids reflect the genetic profile of endometrial tumors and predict patient prognosis 

      Berg, Hege Fredriksen; Hjelmeland, Marta Espevold; Lien, Hilde Eide; Espedal, Heidi; Fonnes, Tina; Srivastava, Aashish; Stokowy, Tomasz; Strand, Elin; Bozickovic, Olivera; Stefansson, Ingunn Marie; Bjørge, Line; Trovik, Jone; Haldorsen, Ingfrid S.; Høivik, Erling Andre; Krakstad, Camilla (Journal article; Peer reviewed, 2021)
      Background: A major hurdle in translational endometrial cancer (EC) research is the lack of robust preclinical models that capture both inter- and intra-tumor heterogeneity. This has hampered the development of new treatment ...

    • Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease 

      Lien, Hilde Eide; Berg, Hege Fredriksen; Halle, Mari Kyllesø; Trovik, Jone; Haldorsen, Ingfrid S.; Akslen, Lars Andreas; Krakstad, Camilla (Journal article; Peer reviewed, 2023)
      Background: Identification of aggressive low-stage endometrial cancers is challenging. So far, studies have failed to pinpoint robust features or biomarkers associated with risk of recurrence for these patients. Methods: ...